cees dekker Things To Know Before You Buy
cees dekker Things To Know Before You Buy
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Human Rad51 filaments on double- and solitary-stranded DNA: correlating typical and irregular varieties with recombination function.
‘It absolutely was basically a make a difference of picking up a reserve on mobile biology and starting to browse. I had come from a environment of ultra-higher vacuums, cryostats and quantum phenomena, and now I was Doing the job at area temperature with molecular biology kits.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
This yielded a breakthrough. In just only some months, we ended up in the position to evaluate transport via an individual one-walled carbon nanotube. Dependant on very low-temperature experiments by an excellent PhD college student in my group, Sander Tans (now a valued colleague and professor at Delft University of Technology by having an active exploration lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with incredibly lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
SMC complexes can go Bodily roadblocks bigger than their ring dimension, indicating a nontopological system for DNA loop extrusion
We use nanofabricated microfluidic constructions to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental purpose of spatial confinement for the molecular and mobile degree. Our assignments contain the following:
Dynamic ParB–DNA interactions initiate and preserve a partition condensate for bacterial chromosome segregation
In 1993, as a young and eager affiliate professor at Delft College of Technologies, I had to begin with focused the analysis initiatives of my team on measuring the electrical conductance of a single conducting-polymer molecule. Inside of two decades, we had produced a device through which only one wire of the phthalocyaninepolysiloxane polymer was connected among two carefully spaced steel nanoelectrodes.
But carbon nanotubes have remained a study topic of considerable desire to lots of. In truth, the outlook on applying carbon nanotubes to make realistic products, in regions for example radio-frequency electronics, digital electronics and flexible electronics, continues to be shiny.
[14] In 2005 Dekker turned involved in Netherlands-extensive discussions about Smart Structure, a movement that he has due to the fact clearly distanced himself from. Dekker advocates that science and religion are usually not in opposition but could be harmonized.
Cees Dekker is Distinguished College Professor at TU Delft. Qualified for a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes in the 1990s. Since 2000, he moved to one-molecule biophysics and nanobiology. His present-day investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, specifically SMC motor protein; and (iii) creating a living synthetic mobile from lifeless molecules. Dekker is really an elected member with the KNAW and fellow on the APS along with the IOP.
Developments in nanotechnology inside the 1990s produced building Digital devices from single molecules a possibility. Cees Dekker recounts how his group designed a room-temperature transistor https://www.ceesdekker.net based on a single carbon nanotube.
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments